The PANAMutyper™ ROS1 Screening Kit is an invitro diagnostic device for detecting 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients.
no. |
ROS1 Fusion Types |
Partner last observed exon |
ROS1 first observed exon |
1 |
CD6-R32 |
CD74 exon 6 |
exon 32 |
2 |
CD6-R34 |
exon 34 |
|
3 |
EZ10-R34 |
EZR exon 10 |
exon 34 |
4 |
SL4-R32 |
SLC34A2 exon 4 |
exon 32 |
5 |
SL4-R34 |
exon 34 |
|
6 |
SL13del-R32 |
SLC34A2 exon 13del |
exon 32 |
7 |
SL13del-R34 |
exon 34 |
|
8 |
SD2-R34 |
SDC4 exon 2 |
exon 32 |
9 |
SD2-R34 |
exon 34 |
|
10 |
SD4-R32 |
SDC4 exon 4 |
exon 32 |
11 |
SD4-R34 |
exon 34 |
|
12 |
TP2-R35 |
TPM3 exon 2 |
exon 35 |
13 |
TP2-R36 |
exon 36 |
|
14 |
TP8-R35 |
TPM3 exon 8 |
exon 35 |
15 |
TP8-R36 |
exon 36 |
|
16 |
GO4-R35 |
GOPC exon 4 |
exon 35 |
17 |
GO4-R36 |
exon 36 |
|
18 |
GO8-R35 |
GOPC exon 8 |
exon 35 |
19 |
GO8-R36 |
exon 36 |
|
20 |
LR16-R35 |
LRIG3 exon 16 |
exon 35 |
FEATURES
PROCEDURE
- Sample preparation
- Extraction of DNA
- Real-time PCR
- Result Analysis
COMPATIBLE SAMPE TYPE
Fresh tissue and biopsy
COMPATIBLE REAL-TIME PCR MACHINE
CFX96
(Bio-Rad)
QuantStudio5
(Thermo Fisher Scientific)
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