Hepatitis B virus (HBV) is a widely spread human infection caused by DNA-containing virus of HBV belonging to the family Hepadnaviridae. At present in accordance with the WHO data the population infected with HBV virus makes 500 million people.
Detection of HBV DNA is used for:
– Early diagnostics of acute viral hepatitis B;
– Detection of latent forms of viral hepatitis B;
– Detection of mutant strains of hepatitis B virus by HBsAg;
– Establishment of diagnosis of chronic viral hepatitis B;
– Monitoring of effectiveness of the antiviral therapy;
ADVANTAGES OF SACACE HBV REAL TIME QUANT KIT
– CE-IVD marked
– Use of the Quantitative Internal Control (concentration reported in Data Card) which represents recombinant DNA-containing-structure which carried through all steps of analysis from nucleic acid extraction to PCR amplification. The presence of quantitative HBV Rec IC allows not only to monitor the extraction procedure and to check possible PCR inhibition but also to verify possible losses of the DNA during extraction procedure thus enabling to calculate precisely the HBV viral load.
– Presence in the reagents supplied with the kit of two positive controls of the extraction: Pos1 HBV low viral load and Pos2 HBV medium viral load that are quantitatively described in Data Card which carried through all steps and allow quality control of the conducted analysis.
– High sensitivity: 20 copies/ml (value obtained using the Magno-Virus extraction kit (Sacace REF K-2-16)
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