Product name
Human Follicle Stimulating Hormone ELISA Kit
Detection method
Colorimetric
Sample type
Serum
Assay type
Sandwich (quantitative)
Sensitivity
600 µlU/ml
Range
0.001 U/ml – 0.1 U/ml
Assay duration
Multiple steps standard assay
Species reactivity
Reacts with: Human
Product overview
ab108678 Follicle Stimulating Hormone Human ELISA Kit is a immunoenzymatic colorimetric method for quantitative determination of Follicle Stimulating Hormone in serum.
Follicle Stimulating hormone (FSH) is a glycoprotein consisting of two subunits with an approximate molecular mass of 35,500 daltons. The alpha-subunit is similar to other pituitary hormones [luteinizing stimulating hormone (LH), thyroid stimulating hormone (TSH) and chorionic gonadotropin (hCG)] while the beta-subunit is unique. The beta-subunit confers the biological activity to the molecule. Stimulation by gonadotropin-releasing hormone (GnRH) causes release of FSH, as well as LH, from the pituitary and is transported by the blood to their sites of action, the testes or ovary. In men, FSH acts on the Sertoli cells of the testis, stimulating the synthesis of inhibin, which appears to specifically inhibit further FSH secretion, and androgen-binding protein. Thus, it indirectly supports spermatogenesis. In women, FSH acts on the granulosa cells of the ovary, stimulating steroidogensis. All ovulatory menstrual cycles have a characteristic pattern of FSH, as well as LH, secretion.
Platform
Microplate
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