Human Thyroxine ELISA Kit (fT4)- 96 Tests
Available on backorder
Expiry Date
Key features and details
Sensitivity: 0.5 ng/ml
Sample type: Serum
Detection method: Colorimetric
Assay type: Competitive
Reacts with: Human
EGP 19,488.00
Available on backorder
Sample type
Serum
Assay type
Competitive
Sensitivity
0.5 ng/ml
Assay duration
Multiple steps standard assay
Species reactivity
Reacts with: Human
Product overview
ab108662, Thyroxine (fT4) Human ELISA Kit is intended for the quantitative determination of Free Thyroxine (fT4) concentration in Human serum.
Thyroxine (T4) or 3,5,3’,5’-tetraiodothyronine is the most commonly measured thyroid hormone for the diagnosis of thyroid function. Thyroxine (T4) has its primary infuence on protein synthesis and oxygen consumption in virtually all tissues but it is also important for growth, development, and sexual maturation. Thyroxine (T4) is synthesized by the thyroid gland and is secreted into the bloodstream. Here the Thyroxine (T4) becomes bound to serum proteins for transport to the cells. The major transport protein is Thyroxine Binding Globulin (TBG) which normally accounts for 80% of the bound Thyroxine (T4). Other thyroid hormone binding proteins are Thyroxine Binding Prealbumin and Albumin. Most of the serum Thyroxine (T4) is bound to these transport proteins leaving only about 0.03% free to exert its effect on cells. It is the free Thyroxine (T4) (fT4) that represents the metabolically active fraction; for this reason the measurement of fT4 concentration is considered to be an indicator of patient thyroid status. Primary hypothyroidism results in underproduction of Thyroxine (T4) by the thyroid gland and consequently an abnormally low circulating fT4 concentration in the blood. Primary hyperthyroidism leads to excessive thyroid production on Thyroxine (T4) and resulting elevated fT4 concentration.
Platform
Microplate
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