PNAClamp™ KRAS Kit (Ver.4) 25 test/kit

Panagene
Availability:

Available on backorder


Expiry Date

N/A

KRAS mutation is found in several cancers such as colorectal, lung, thyroid, pancreatic, cholangiocarcinoma. The KRAS mutations are often found on codons 12 and 13 of the exon 2, and lead to abnormal change of growth signal of the p21-ras protein. This abnormal change involved with cell growth and division may cause the process of cancer development by delivering the signal in excess. Existence of KRAS mutations is often related with a prognostic marker to drug response. For example, KRAS mutation is considered a strong prognostic marker for drug response of tyrosine kinase inhibitors such as gefitinib (Iressa) or erlotinib (Tarceva). Recently, KRAS mutation is often detected in colorectal cancer and may be related with drug response to cetuximab (Erbitux) or panitumumab (Vectibix) that is used for colon cancer therapy. Therefore, examination of KRAS mutation is needed to determine drug resistance of patients with colorectal or lung cancers and will be helpful for cancer therapies.

EGP 57,000.00

Available on backorder

Total 40 KRAS mutations can be detected.

 

 Mutations

Size 

 Codon 12

Codon 13 

Codon 59 

Codon 61 

Codon 117 

Codon 146 

 25 tests

 6

 6

 5

 12

 4

 7

 


FEATURES

  • 01High sensitivity and specificity even with small amount of DNA (2% LOD with 10 ng wild/mutant type mixed DNA)
  • 02Real-Time PCR based ready-to-use kit
  • 03Short running time (within 3 hours)

PROCEDURE

  1. Sample preparation
  2. Extraction of DNA
  3. Real-time PCR
  4. Result Analysis

COMPATIBLE SAMPE TYPE

– FFPE tissue

COMPATIBLE REAL-TIME PCR MACHINE

  1. CFX96(Bio-Rad)
  2. ABI7500(Thermo Fisher Scientific)
  3. StepOnePlus (Thermo Fisher Scientific)
  4. LightCycler 480II (Roche)
  5. ABI7900HT (Thermo Fisher Scientific)
  6. Rotor-Gene Q (Qiagen)

Based on 0 reviews

0.0 overall
0
0
0
0
0

Be the first to review “PNAClamp™ KRAS Kit (Ver.4) 25 test/kit”

There are no reviews yet.

Shipping Policy

Payment & Delivery:

  1. You agree to provide valid shipping address, Email address and phone numbers, if we received false information, we are not responsible to any action happen to the product delivered.
  2. Delivery period may be not known as each item has its own delivery period as well as the seller delivery terms are not the same, so we don't share exact delivery period before we get confirmed information concerning this part, you don't need to confirm your order before receiving such information.
  3. Some items will have certain Expiry dates, if this information is available on the item, we will share it, if not, please request the expiry date after adding the item to the cart.
  4. Some items have expiry date that you don't satisfied with, So Please request new expiry date to the same item.
  5. When placing an order, you will confirm your personal information, shipping and billing address, payment methods, and the subtotal amount of the order.
  6. You will receive an email confirming your order with your order number, if you wish to contact support you will need to use the specific order number.
  7. Payment methods are the following:

                         A- Online payment with credit card (we accept Visa  and MasterCard )

                         B-Cash Upon Delivery

                         C- Bank deposit in our bank account

  1. You agree to provide valid and accurate payment information.

Refund Policy

  1. The buyer has the full rights to return products that are shipped from BGENZ.com.

Cancellation / Return / Exchange Policy

Return Policy:

  1. The buyer has the full rights to return products that are shipped from BGENZ.com.
  2. Products can be returned within 14 days of receipt of shipment in most cases.
  3. Some products have different policies or requirements associated with them.
  4. Some kits or reagents will need technical report with pictures showing the defect or malfunction.
  5. You have the right to choose to replace the product or refund your money.

General Inquiries

There are no inquiries yet.