PNAClamp™ PIK3CA Kit 25 test/kit
Available on backorder
Expiry Date
N/APIK3CA mutation activates PI3K (Phosphatidylinositol 3-kinase) protein and PI3K activates several signaling pathways of tyrosine kinase receptors. Activated tyrosine kinase represses the function and excitometabolism of protein which inhibits cell survival and division. These abnormal changes initiate the process of cancer development by activating the protein involved in cell growth. Point mutations in PIK3CA are detected with ca. 80% of frequency in exon 9 (interpreted as helical part of PI3K protein) and exon 20 (interpreted as kinase part), while other types of mutations are also seen in many different locations. PIK3CA mutations are found with 25 to 40 % frequency in various types of cancer like colorectal cancer, gastric cancer, lung cancer, brain cancer, endometrial cancer, ovarian cancer, breast cancer, and more.
PNAClamp™ PIK3CA Mutation Detection Kit utilizes modified PCR technology, using optimized PNA probes that tightly bind to wild type DNA templates. This tight binding to the wild type DNA templates result in no amplification of the wild type DNA template in PCR reaction while the mutated genes, especially with SNPs, PCR amplification is processed for multiplication of the mutated DNA sequences.
EGP 57,000.00
Available on backorder
Total 15 PIK3CA mutations can be detected.
|
Mutations |
Size |
||||
|
Codon 542 |
Codon 545 |
Codon 546 |
Codon 1047 |
Codon 420 |
25 tests |
|
3 |
4 |
4 |
3 |
1 | |
FEATURES
PROCEDURE
- Sample preparation
- Extraction of DNA
- Real-time PCR
- Result Analysis
COMPATIBLE SAMPE TYPE
– Plasma
COMPATIBLE REAL-TIME PCR MACHINE
- CFX96 (Bio-Rad)
- ABI7500 (Thermo Fisher Scientific)
- LightCycler 480II (Roche)
- Rotor-Gene Q (Qiagen)
Based on 0 reviews
Be the first to review “PNAClamp™ PIK3CA Kit 25 test/kit”
Shipping Policy
Payment & Delivery:
- You agree to provide valid shipping address, Email address and phone numbers, if we received false information, we are not responsible to any action happen to the product delivered.
- Delivery period may be not known as each item has its own delivery period as well as the seller delivery terms are not the same, so we don't share exact delivery period before we get confirmed information concerning this part, you don't need to confirm your order before receiving such information.
- Some items will have certain Expiry dates, if this information is available on the item, we will share it, if not, please request the expiry date after adding the item to the cart.
- Some items have expiry date that you don't satisfied with, So Please request new expiry date to the same item.
- When placing an order, you will confirm your personal information, shipping and billing address, payment methods, and the subtotal amount of the order.
- You will receive an email confirming your order with your order number, if you wish to contact support you will need to use the specific order number.
- Payment methods are the following:
A- Online payment with credit card (we accept Visa and MasterCard )
B-Cash Upon Delivery
C- Bank deposit in our bank account
- You agree to provide valid and accurate payment information.
Refund Policy
- The buyer has the full rights to return products that are shipped from BGENZ.com.
Cancellation / Return / Exchange Policy
Return Policy:
- The buyer has the full rights to return products that are shipped from BGENZ.com.
- Products can be returned within 14 days of receipt of shipment in most cases.
- Some products have different policies or requirements associated with them.
- Some kits or reagents will need technical report with pictures showing the defect or malfunction.
- You have the right to choose to replace the product or refund your money.
General Inquiries
There are no inquiries yet.
There are no reviews yet.