{"id":22615,"date":"2021-01-05T12:14:05","date_gmt":"2021-01-05T09:14:05","guid":{"rendered":"https:\/\/bgenz.com\/Bio\/product\/pnaclamp-idh1-kit-25-test-kit\/"},"modified":"2021-01-05T13:38:58","modified_gmt":"2021-01-05T10:38:58","slug":"pnaclamp-idh1-kit-25-test-kit","status":"publish","type":"product","link":"https:\/\/bgenz.com\/Bio\/product\/pnaclamp-idh1-kit-25-test-kit\/","title":{"rendered":"PNAClamp\u2122 IDH1 Kit 25 test\/kit"},"content":{"rendered":"
\n

Total 5 IDH1 mutations can be detected.<\/span><\/p>\n

\u00a0<\/p>\n

<\/p>\n\n\n\n\n\n
\n

\u00a0Mutations<\/span><\/p>\n<\/td>\n

\n

\u00a0Size<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Codon 132\u00a0<\/span><\/p>\n<\/td>\n

\n

25 tests\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

5\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/span><\/div>\n

<\/div>\n<\/div>\n
\n

FEATURES<\/p>\n

\n
    \n
  • 01<\/span>High sensitivity and specificity even with small amount of DNA (1% LOD with 10 ng wild\/mutant type mixed DNA)<\/span><\/li>\n
  • 02<\/span>Real-Time PCR based ready-to-use kit<\/span><\/li>\n
  • 03<\/span>Short running time (within 3 hours)<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n

    PROCEDURE<\/h4>\n
      \n
    1. Sample preparation<\/span><\/o:p><\/span><\/li>\n
    2. Extraction of DNA<\/span><\/o:p><\/span><\/li>\n
    3. Real-time PCR<\/span><\/o:p><\/span><\/li>\n
    4. Result Analysis<\/span><\/o:p><\/span><\/li>\n<\/ol>\n

      COMPATIBLE SAMPE TYPE<\/h4>\n
      – FFPE tissue
      – Fresh tissue<\/div>\n

      COMPATIBLE REAL-TIME PCR MACHINE<\/h4>\n
        \n
      1. CFX96<\/span>(Bio-Rad)<\/span>
        <\/li>\n
      2. ABI7500 <\/span>(Thermo Fisher Scientific)<\/span>
        <\/li>\n
      3. LightCycler 480II <\/span>(Roche)<\/span>
        <\/li>\n
      4. Rotor-Gene Q <\/span>(Qiagen)<\/span>
        <\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

        Mutations of IDH1 (isocitrate dehydrogenase 1,IDH1) can be found in glioblastoma and myeloproliferative neoplasm. Detection of IDH1mutations can be a positive predictor of a prognosis and a molecular marker for glioblastoma patients. On the other hand, it is reported that IDH1 mutations correlate with poor prognosis in myeloproliferative neoplasm.
        PNAClamp\u2122 IDH1 Mutation Detection Kit is a new member of somatic mutation detection kits utilizing PNA-mediated PCR Clamping technology, and can help patients choose the right medicine and monitor prognosis.<\/p>\n","protected":false},"featured_media":22608,"comment_status":"open","ping_status":"closed","template":"","meta":{"spay_email":""},"_links":{"self":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/product\/22615"}],"collection":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/comments?post=22615"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/media\/22608"}],"wp:attachment":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/media?parent=22615"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}