{"id":22620,"date":"2021-01-05T12:14:06","date_gmt":"2021-01-05T09:14:06","guid":{"rendered":"https:\/\/bgenz.com\/Bio\/product\/pnaclamp-tert-kit-25-test-kit\/"},"modified":"2021-01-05T13:18:35","modified_gmt":"2021-01-05T10:18:35","slug":"pnaclamp-tert-kit-25-test-kit","status":"publish","type":"product","link":"https:\/\/bgenz.com\/Bio\/product\/pnaclamp-tert-kit-25-test-kit\/","title":{"rendered":"PNAClamp\u2122 TERT Kit 25 test\/kit"},"content":{"rendered":"
\n

The PNAClamp\u2122 TERT Mutation Detection Kit is an in vitro diagnostic reagent for detecting 2 different TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from patients with cancer such as the central nervous system, bladder, thyroid, skin, etc.<\/span>\u00a0<\/p>\n\n\n\n\n\n
\n

Mutation\u00a0<\/span><\/p>\n<\/td>\n

\n

Nucleotide change\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u00a0C228<\/span><\/p>\n<\/td>\n

\n

c.1-124C>T\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u00a0C250<\/span><\/p>\n<\/td>\n

\n

c.1-146C>T\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\n

FEATURES<\/p>\n

\n
    \n
  • 01<\/span>Detection of 2 TERT promoter mutations<\/span><\/li>\n
  • 02<\/span>High sensitivity, specificity and reproducibility<\/span><\/li>\n
  • 03<\/span>Short running time<\/span><\/li>\n
  • 04<\/span>Simple workflow<\/span><\/li>\n
  • 05<\/span>Easy result reading by automatic analyzing program<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n

    PROCEDURE<\/h4>\n
      \n
    1. Sample preparation<\/span><\/li>\n
    2. Extraction of DNA<\/span><\/li>\n
    3. Real-time PCR<\/span><\/li>\n
    4. Result Analysis<\/span><\/li>\n<\/ol>\n

      COMPATIBLE SAMPE TYPE<\/h4>\n
      – Formalin-fixed paraffin-embedded(FFPE) tissue
      – Fresh tissue and biopsy sample<\/div>\n

      COMPATIBLE REAL-TIME PCR MACHINE<\/h4>\n

      CFX96<\/span>
      (Bio-Rad)<\/span><\/p>\n

      QuantStudio5<\/span>
      (ThermoFisher Scientific)<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

      The presence of TERT mutation is a prognostic and predictive biomarker in patients with cancer such as the central nervous system, bladder, thyroid, skin, etc., associated with tumor recurrence and survival.<\/p>\n

      With its features of detection limit as low as 5% copies\/rxn, the PNAClamp\u2122 TERT Mutation Detection Kit is the qualitative diagnostic test kit which is able to detect 2 different types of TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues using peptide nucleic acid (PNA)-mediated real-time PCR clamping technology.<\/p>\n","protected":false},"featured_media":22608,"comment_status":"open","ping_status":"closed","template":"","meta":{"spay_email":""},"_links":{"self":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/product\/22620"}],"collection":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/comments?post=22620"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/media\/22608"}],"wp:attachment":[{"href":"https:\/\/bgenz.com\/Bio\/wp-json\/wp\/v2\/media?parent=22620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}