PNAClamp™ NRAS Kit 25 test/kit

Panagene
Availability:

Available on backorder


Expiry Date

N/A

NRAS mutation is found in several cancers such as melanoma (13~25%), colorectal cancer (1~6%), lung cancer (1%), thyroid cancer (7%) and hepatocellular carcinoma (10%). It is know that the drug response against colorectal cancer medicine such as Erbitux and Cetuximab decreased and the prognosis of the metastatic colorectal cancer patient is bad if the patient has NRAS mutation.

EGP 57,000.00

Available on backorder

Total 43 NRAS mutations can be detected.

 

 Mutations

Size 

 Codon 12

Codon 13 

Codon 59 

Codon 61 

Codon 117 

Codon 146 

25 tests 

 9

 10

 3

 12

 4

 5

 

FEATURES

  • 01High sensitivity and specificity even with small amount of DNA (2% LOD with 10 ng wild/mutant type mixed DNA)
  • 02Real-Time PCR based ready-to-use kit
  • 03Short running time (within 3 hours)

PROCEDURE

  1. Sample preparation
  2. Extraction of DNA
  3. Real-time PCR
  4. Result Analysis

COMPATIBLE SAMPE TYPE

– FFPE tissue

COMPATIBLE REAL-TIME PCR MACHINE

  1. CFX96 (Bio-Rad)
  2. ABI7500 (Thermo Fisher Scientific)
  3. StepOnePlus (Thermo Fisher Scientific)
  4. LightCycler 480II (Roche)
  5. ABI7900HT (Thermo Fisher Scientific)
  6. Rotor-Gene Q (Qiagen)